methylene diphenyl diisocyanate un number

This section is based on three sources for information (harmonised classification and labelling (CLH), REACH registrations and CLP notifications). This fact sheet answers the most frequently asked health questions (FAQs) about toluene diisocyanate (TDI) and methylenediphenyl diisocyanate (MDI). Substances may be grouped together under a specific regulatory activity for more efficient risk management and legislative processing (e.g. (3) MDI is the usual abbreviation for monomeric methylene diphenyl diisocyanate, (CAS# 101-68-8). We apologise for the inconvenience in the meantime. Section 1 - Identification of the substance/mixture and of the company/undertaking The examples provided are generic examples and may not apply to the specific substance you are viewing. The precautionary measures and guidance on safe use are as submitted to ECHA by registrants under the REACH Regulation. ECHA has no public registered data indicating whether or into which articles the substance might have been processed. A substance may have its use restricted to certain articles or products and therefore not all the examples may apply to the specific substance. The Waste Framework Directive aims to protect the environment and human health from the generation and management of waste and to improve efficient use of resources. If generated, an InChI string will also be generated and made available for searching. Additionally, if available, information on the use of the substance and how consumers and workers are likely to be exposed to it can also be displayed here. MDI and other isocyanates may also cause hypersensitivity pneumonitis, another allergic lung ... Methylene diphenyl diisocyanate (MDI) 0.051 (0.005 ppm) 0.2 (0.02 ppm) 0.005 ppm . 215–540–4, is covered by three harmonisations: 005–011–00–4; 005–011–01–1 and 005–011–02–9), CLH information cannot be displayed in the InfoCard as the difference between the CLH classifications requires manual interpretation or verification. Manage accidents and report an accident in accordance with all local, state and federal regulations. Stable under recommended storage conditions. 2(b)(i), Directive 98/24/EC on Protection of Workers from Chemical Agent-related Risks, 5 May 1998 (Table 3 of Annex VI to CLP, as amended), EU. Release to the environment of this substance can occur from industrial use: manufacturing of the substance, formulation of mixtures and for thermoplastic manufacture. This information has not been reviewed or verified by ECHA, and may change without prior notice. General Description Diphenylmethane-4,4-diisocyanate is a light yellow colored solid. The CLP Regulation uses the UN Global Harmonised System (GHS) and European Union Specific Hazard Statements (EUH). Methylenediphenyl 4,4'-Diisocyanate . Chemical Agents: Annexes I & II, Dir. Precautionary statements - describe recommended measures to minimise or prevent adverse effects resulting from exposure to a hazardous product or improper storage or handling of a hazardous product. Hazard statements were adapted to improve readability and may not correspond textually to the hazard statements codes description in the European Union Specific Hazard Statements (EUH) or the. This fact sheet is one in a series of summaries about hazardous substances and their health effects. The freezing point of 4,4’ … This substance is used in the following products: coating products, inks and toners, polymers and cosmetics and personal care products. Guidance To help minimize the formation of a dimer, an insoluble white solid that may impact the quality of the product, 4,4’-methylene diphenyl diisocyanate (MDI) is usually stored and transported in drums at temperatures below 41°F (5°C). ... or the UN Global Harmonised System ... Methylene diphenyl diisocyanate . It covers their hazardous properties, classification and labelling, and information on how to use them safely. h�bbd``b`� �@�q+�`��q��9� H��- � �=�P� b9 ��)�@�4�Ҍ�����$)'�3.�` ��G Union List of Authorized Substances: Annex I, Plastics Food Contact Regulation 10/2011/EU, as amended by Regulation 2020/1245/EU, 3 September 2020, EU. Guidance on safe use - recommendations by substance registrant on the proper use of the substance in various situations. Here you can find all of the regulations and regulatory lists in which this substance appears, according to the data available to ECHA. 590 Revision Date: 1/8/2019 Version: 10.0 GHS Compliant . EU. Emergency Response Guidebook 2016. This Action Plan addresses the use of methylene diphenyl diisocyanate (MDI) and related compounds (See Appendix 1) in products that may result in consumer and general population ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment. in case of consumer and professional uses). … Polymeric Diphenylmethane Diisocyanate (pMDI) 9016-87-9 50 – 60 4, 4’ Diphenylmethane Diisocyanate (MDI) 101-68-8 35 – 45 2, 4’ Diphenylmethane Diisocyanate (MDI) 5873-54-1 1 – 5 SECTION 4: FIRST AID MEASURES Eye Contact Immediately flush eyes with running water for a minimum of 15 minutes. %PDF-1.5 %���� This section provides an overview of the calculated volume at which the substance is manufactured or imported to the European Economic Area (EU28 + Iceland, Liechtenstein and Norway). The EC or list number is the primary substance identifier used by ECHA. This section highlights four regulatory activities or outcomes under REACH – Registration, Evaluation, Authorisation and Restriction of Chemicals – Regulation (EC) No 1907/2006: Please note: The identification of relevant regulatory activities and outcomes is done automatically and without manual verification. Hazardous Substances - Art. MDA is treated with phosgene to give MDI. InfoCards are updated when new information is available. National Center for Environmental Assessment, Office of Research and Development, … 1. of . This list contains substances to which pregnant workers and workers who have recently given birth or are breastfeeding may not be exposed. Reuzel PGJ, Arts JHE, Kuypers MHM, Kuper CF (1990) Chronic toxicity/carcinogenicity inhalation study of polymeric methylene diphenyl diisocyanate aerosol in rats. Release to the environment of this substance can occur from industrial use: formulation of mixtures, formulation in materials, for thermoplastic manufacture and in the production of articles. The molecular formula identifies each type of element by its chemical symbol and identifies the number of atoms of each element found in one discrete molecule of the substance. Please upgrade your Internet Explorer to a newer version. For more information, call the ATSDR Information Center at 1-800-232-4636. the electronic edition of the Official Journal of the European Union should be consulted. REACH registered substance data was upgraded on 9th November. If a substance is classified under multiple CLH entries, a link to the C&L Inventory is provided to allow users to view CLH information associated with the substance and no text is automatically generated for the InfoCard. Substances according to Hazardous Waste Properties: Annex III, Directive 2008/98/EC, 22 November 2008, amended by Directive 2018/851/EU, 14 June 2018, Registration, Evaluation, Authorisation and Restriction of Chemicals, Chemical Agents Directive and Carcinogens or Mutagens Directive, Plastic Materials and Articles Regulation, Protection of Pregnant and Breastfeeding Workers Directive, Safety and/or Health Signs at Work Directive, EC Inventory, Pre-Registration process, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, Pre-Registration process, Cosmetic Products Regulation, Annex II - Prohibited Substances, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, C&L Inventory, Pre-Registration process, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, 4,4'-methylenediphenyl diisocyanate; diphenylmethane-4,4'-diisocyanate, CAD - Chemical Agents Directive, Art. In these cases, Infocards may not identify all substances in the group.Therefore it does not represent official and legally–binding information. Other release to the environment of this substance is likely to occur from: indoor use (e.g. In order to process your orders without delay, we request that you provide the required business documentation to purchase this product. This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 000 per annum. Please note: Precautionary measures and guidance on safe use concern the use and handling of the specific substance as such, not of the presence of the substance in other articles or mixtures. To confirm if a substance is covered by a specific regulatory action the official publication, e.g. The CAS number is the substance numerical identifier assigned by the Chemical Abstracts Service, a division of the American Chemical Society, to substances registered in the CAS registry database. The CLP Regulation makes sure that the hazards presented by chemicals are clearly communicated to workers and consumers in the European Union. It does not represent a new labelling, classification or hazard statement, neither reflect other factors that affect the susceptibility of the effects described, such as duration of exposure or substance concentration (e.g. LEL:. More information about CAS and the CAS registry can be found here. REACH regulation aims to improve the protection of human health and the environment from the risks that can be posed by chemicals. CHEMTREC operators are available 24 hours a day, seven days a week. no data available. Methylenediphenyl diisocyanate (MDI) including the following specific isomers (See group members): Previous consultations on ECHA’s Executive Director Requests to the Committees, Applications for authorisation consultations, Harmonised classification and labelling consultations, ECHA Executive Director’s requests related to the CLH process, Consultation on potential candidates for substitution, Consultation on derogation to the exclusion criteria, ECHA's Executive Director Requests to the Committees, Consultation on a draft recommendation for amendment of Authorisation List entries, Consultations in the authorisation process, Occupational exposure limits - Call for comments and evidence, Occupational exposure limits - Previous calls for comments and evidence, Occupational exposure limits – Consultations on OEL recommendation, Derogations for the protection of cultural heritage, ECHA's current activities on restrictions, ECHA's completed activities on restriction, Information on Candidate List substances in articles table, Information from the Existing Substances Regulation (ESR), PBT/vPvB assessments under the previous EU chemicals legislation, Adopted opinions and previous consultations on applications for authorisation, Adopted opinions on restriction proposals, Mapping exercise – Plastic additives initiative, Occupational exposure limits substance evaluations, List of substances subject to POPs Regulation, Small and Medium-sized Enterprises (SMEs), Practical examples of chemical safety reports. DOT Environmentally Hazardous Substance, N.O.S. ECHA maintains the C&L Inventory, but does not review or verify the accuracy of the information. First-aid measures 0.02 . 2(b)(i) - Hazardous Agents, Cosmetic Products Regulation, Annex II - Prohibited Substances, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, FCM and Articles Regulation, Annex I - Authorised Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, Workplace Signs - minimum requirements & signs on containers and pipes, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Fertiliser Regulation- Annex I, E.3 (chelating and complexing agents), Substances of very high concern identification, Recommendation for the Authorisation List, Getting started with EU chemicals legislation, Classification of substances and mixtures, Harmonised classification and labelling (CLH). This substance is used in the following products: adhesives and sealants and coating products. The classifications of the substances listed in the database are based on their harmonized classifications per Table 3 of Annex VI to the CLP Regulation (1272/2008/EC). Substances intended to be restricted and entered in Annex XVII to REACH. Release to the environment of this substance can occur from industrial use: for thermoplastic manufacture, in the production of articles, in processing aids at industrial sites, formulation of mixtures, formulation in materials and as an intermediate step in further manufacturing of another substance (use of intermediates). An additional source of information is also CHEMTREC, which can be reached at 1-800-424-9300. This substance has been found in the following regulatory activities (directly, or inheriting the regulatory context of a parent substance): This list represents a calculated inventory of substances based on the list of harmonized substances contained in Table 3 of Annex VI to the CLP Regulation (1272/2008/EC). The EU Ecolabel may not be awarded to substances or mixtures classified as such. 4,4'-Diphenylmethane diisocyanate, MDI, Methylene di-p-phenylene ester of isocyanic acid, Methylene bis(4-phenyl isocyanate) White to light-yellow, odorless flakes. CAS number: 101–68–8 NIOSH REL: 0.05 mg/m 3 (0.005 ppm) TWA, 0.2 mg/m 3 (0.020 ppm) 10-minute CEILING. In that case, the ATP (Adaptation to Technical Progress) number is displayed. Some substance identifiers may have been claimed confidential, or may not have been provided, and therefore not be displayed. The molecular structure is based on structures generated from information available in ECHA’s databases. While the harmonized list covers many hazardous substances, other ones not listed may also meet the classification criteria in accordance with the CLP. 2(b)(i) - Hazardous Agents, Cosmetic Products Regulation, Annex II - Prohibited Substances, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, FCM and Articles Regulation, Annex I - Authorised Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, Physical, Biological and Chemical Agents & Processes and Work, Workplace Signs - minimum requirements & signs on containers and pipes, Waste Framework Directive, Annex III - Waste - Hazardous Properties. Impurities or additives: When a specific critical property is calculated from industry data and where the majority of data submitters have indicated that the property relates to cases containing impurities and/or additives, then the respective critical property icon is modified with an asterisk (*). CAS Number 101-68-8 Synonym(s) p,p'-Diphenylmethane diisocyanate; p,p'-Methylenebis[phenyl isocyanate]; Bis(p-isocyanatophenyl)methane; Diphenylmethane diisocyanate; Diphenylmethane p,p'-diisocyanate; Methylenebis[p-phenyl isocyanate]; 4,41-MDI; MDI; Monomeric MDI; NCI-C50668 ... Reference Exposure Levels for Methylene Diphenyl Diisocyanate … Other relevant information includes the following: To see the full list of notified classifications and to get more information on impurities and additives relevant to classification please consult the C&L Inventory. "�E��z���!9�%��E$�0?�DJrC� The per substance REACH registration status is being calculated and will be made available as soon as possible. Biocidal Products Committee opinions on active substance approval, National authorisation and mutual recognition, Understanding the Waste Framework Directive, Tools to prepare and submit SCIP notifications, List of substances subject to the POPs Regulation, Draft recommendation for inclusion in the Authorisation List and consultation, Submitted restrictions under consideration, Harmonised classification and labelling targeted consultations, Consultations on ECHA Executive Director’s requests, PACT - Public Activities Coordination Tool, Information on Candidate List substances in articles, Candidate List of substances of very high concern for Authorisation, Registry of restriction intentions until outcome, Registry of SVHC intentions until outcome, Table of harmonised entries in Annex VI to CLP, Occupational exposure limits - Activity list, Harmonised classification and labelling (RAC), Chapter R.12: Use Descriptor system of ECHA Guidance on information requirements and chemical safety assessment, Candidate list of substances of very high concern for authorisation, Guidance on the safe use of the substance, PACT - Public activities Co-ordination Tool, Persistence, bioaccumulation and toxicity assessment, RMOA - Regulatory Management Options Analysis, CAD - Chemical Agents Directive,Art. ��#�Y^�7��b�4.F��}��:WI���1w�y�(_W�q2.H�������e�B�r�|�I��|>�Ք^ Gtb�+������Ϸ�9z�W�D����4N��.H�B����+�-�J��t|Rw�����. The 2016 Emergency Response Guidebook, developed jointly by Transport Canada (TC), the U.S. Department of Transportation (DOT), the Secretariat of Communications and Transport of Mexico (SCT) and with the collaboration of CIQUIME (Centro de Información Química para Emergencias) … Furthermore, some substances can be found in an article, but with unlikely exposure (e.g. Methylene diphenyl diisocyanate (MDI) in commercial form typically exists as a mixture of 4,4'-MDI (monomer) and certain oligomers of MDI (Encyclopedia of Chemical Technology, 1983). The EC Number is the numerical identifier for substances in the EC Inventory. This information is only displayed if the substance is well-defined, its identity is not claimed confidential and there is sufficient information available in ECHA’s databases for ECHA’s algorithms to generate a molecular structure. 101 0 obj <>/Filter/FlateDecode/ID[<16B2F27BCE126B46B9EB2A6FD19D8AB1>]/Index[80 38]/Info 79 0 R/Length 96/Prev 135164/Root 81 0 R/Size 118/Type/XRef/W[1 2 1]>>stream Gas concentrations are in percent by volume. More information about Classification and Labelling is available in the Regulations section of ECHA website. Brain injury, 8(3):285–294. 0 Such notifications are required for hazardous substances, mixtures, or articles, manufactured or imported at over 1 kg per annum. The Support section provides tools and practical guidance to companies which have responsibilities under the EU chemicals legislation. The purpose of the information provided under this section is to highlight the substance hazardousness in a readable format. BPR regulation aims to improve the functioning of the biocidal products market in the EU, while ensuring a high level of protection for humans and the environment. Substances which have been registered and can be placed on the EEA market by those companies with a valid registration. If no EU harmonised classification and labelling exists and the substance was not registered under REACH, information derived from classification and labelling (C&L) notifications to ECHA under CLP Regulation is displayed under this section. • MDI and TDI Nomenclature, Gilbert International Limited 2001, GIL Report Number 2001/B, B. Tury, D.S. MDI is a precursor to many polyurethane foams. Note that this list is not exhaustive. The POPs Regulation bans or severely restricts the production and use of persistent organic pollutants in the European Union. 6(6), Reg. Reidy TJ, Bolter JF (1994) Neuropsychological toxicology of methylene diphenyl diisocyanate: a report of five cases. restriction on "Lead and its compounds"). 0.07 STEL . Details of substance evaluation by member state competent authorities. This substance is used for the manufacture of: chemicals. For a detailed overview on identified uses and environmental releases, please consult the registered substance factsheet. C&L Inventory . Methylene diphenyl diisocyanate; Methylenebis(4-isocyanatobenzene) Methylenebis(4-phenyl isocyanate) Methylenebis(4-phenylene isocyanate) Methylenebis(phenylisocyanate) Methylenebis(phenylisocyanate) (MDI) Methylenebis(p-phenyl isocyanate) Methylenebis(p-phenylene isocyanate) Methylenebisphenylene diisocyanate… Methylene-diphenyl-diisocyanate (MDI) 101-68-8 OSHA PEL-TWA 0.02 ppm ACGIH TLV -TWA 0.005 ppm 2 In AFL-CIO v. OSHA 965 F. 2d 962 (11th Cir. The date of the last update corresponds to the publication date of the InfoCard and not necessarily to the date in which the update occurred in the source data. Use descriptors are adapted from ECHA guidance to improve readability and may not correspond textually to descriptor codes described in Chapter R.12: Use Descriptor system of ECHA Guidance on information requirements and chemical safety assessment. A substance identified primarily by an EC or list number may be linked with more than one CAS number, or with CAS numbers that have been deleted. When information is available in all sources, the first two are displayed as a priority. This substance is used by consumers, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing. Action Plan [RIN 2070-ZA15] I. Overview . This substance is used in the following products: adhesives and sealants and coating products. Use … It has a CASRN of 9016-87-9. More information about the EC Inventory can be found here. Current OSHA PEL: 0.2 mg/m 3 (0.02 ppm) CEILING 1989 OSHA PEL: Same as current PEL 1993-1994 ACGIH TLV: 0.051 mg/m 3 (0.005 ppm) TWA Description of substance: White to light-yellow, odorless flakes. Resources for Diisocyanates Emergency Response h�b```f``�d`e`�p``@ �(GCT䎒��N]���eX2�v2�aig�e`H�����l R�,����`�Wa��fH�l�۶��ʚå���PB+!� cEsE�[EGG�y{sxGP���+�*p���Ӟ ia � ��2�3,�[�3A_!��&i�Lf�����x��xO�%0�Hi: ���y@����X����"�Ϩ ` �3?# This is unique source of information on the chemicals manufactured and imported in Europe. Methylene Diphenyl Diisocyanate (MDI) And Related Compounds . The “polymeric” forms of MDI, which typically consist of 30-70 percent monomeric diphenylmethane diisocyanate and the balance in higher molecular weight fractions (CAS # 5873-54-1) may at times be generically … disodium tetraborate EC no. 10. The source of the information is mentioned in the introductory sentence of the hazard statements. Examples include recommended measures on fire-fighting, transport and recycling and disposal. … the electronic edition of the Official Journal of the European Union. 1992), the court overturned OSHA’s 1989 Air Contaminants Rule, including the 11. endstream endobj startxref 7 and points 2 and 3 of the Annex to Directive 94/33/EC, to which young persons (under 18 years of age) may not be exposed at the workplace. What is the Classification and Labelling Inventory? The content of monomeric MDI generally is between 45% and 65% on a w/w basis (Mobay, 1983). This website uses cookies to ensure you get the best experience on our websites. It is possible that a harmonisation is introduced through an amendment to the CLP Regulation. If at least one company has indicated that the substance classification is affected by impurities or additives, this will be indicated by an informative sentence. This substance is used in the following products: adhesives and sealants and coating products. Environmental Protection Agency. This site is not fully supported in Internet Explorer 7 (and earlier versions). Substances for which classification and labelling data have been notified to ECHA by manufacturers or importers. Diagnosis of diisocyanate asthma 203 Appendices (David I. Bernstein) 203 Reading217 4 The environment 229 R E Bailey, A Gard, K H den Haan, F Heimbach, D Pemberton, H Tadokoro, M Takatsuki and Y Yakabe A general approach to environmental risk assessment 229 Exposure 233 Sources of exposure 233 … Public (risk management) activities co-ordination table. These notifications can be provided by manufacturers, importers and downstream users. The Prior Informed Consent Regulation administers the import and export of certain hazardous chemicals and places obligations on companies who wish to export these chemicals to non-EU countries. A flammable liquid.Isocyanates and thioisocyanates, such as DIPHENYLMETHANE-4,4'-DIISOCYANATE, are incompatible with many classes … Other release to the environment of this substance is likely to occur from: indoor use and outdoor use resulting in inclusion into or onto a materials (e.g. 4,4-Methylene Diphenyl Diisocyanate (MDI), All Isomers CAS Registry Number 101-68-8 1,6-Hexamethylene Diisocyanate (HDI), All Isomers CAS Registry Number 822-06-0 Prepared by Toxicology, Risk Assessment, and Research Division Development Support Document Proposed, March 6, 2019 REACH registration dossiers have greater data requirements (such as supporting studies) than do notifications under CLP. Methylenedi-p-phenyl diisocyanate 0.005 ppm TWA 0.005 ppm TWA; 0.05 mg/m3 TWA 75 mg/m3 IDLH 0.02 ppm Ceiling; 0.2 mg/m3 Ceiling Diphenylmethane-2,4'-diisocyanate none listed none listed none listed 2,6-Di-tert-butyl-p-cresol 2 mg/m3 TWA (inhalable fraction and vapor) 10 mg/m3 TWA none listed ECHA organises consultations to get feedback from all interested parties and to gather the widest possible range of scientific information for the regulatory processes. This substance is used in the following areas: formulation of mixtures and/or re-packaging. According to the harmonised classification and labelling (ATP01) approved by the European Union, this substance causes serious eye irritation, is harmful if inhaled, is suspected of causing cancer, may cause damage to organs through prolonged or repeated exposure, causes skin irritation, may cause an allergic skin reaction, may cause allergy or asthma symptoms or breathing difficulties if inhaled and may cause respiratory irritation. The substance identifiers displayed in the InfoCard are the best available substance name, EC number, CAS number and/or the molecular and structural formulas. The annexes to this directive provide detailed information about the minimum requirements for all safety and health signs. Table 3 of Annex VI to CLP Regulation); and (2) the Candidate List of substances of very high concern (SVHC). This section provides links to the list of precautions (precautionary statements) and to the guidance on safe use, if they have been provided in REACH registration dossiers. IDH number: 1506861 Product name: LOCTITE HB E202 known as PURBOND HB E202 Page 6 of 6 International Air Transportation (ICAO/IATA) It is the responsibility of the substance manufacturers and importers to consult official publications, e.g. %%EOF … Gilbert, D.C. Allport, January 2001 ... MDI methylene diphenyl diisocyanate technical MDI pure MDI diisocyanatodiphenylmethane crude MDI monomeric MDI methylenediphenylene diisocyanate polymethylene polyphenyl … If available, additional information on classification and labelling (C&L) is derived from REACH registration dossiers submitted by industry. This list contains biological and chemical agents, in accordance with Art. 4. 117 0 obj <>stream Identification number: UN 3082 Packing group: III DOT Hazardous Substance(s): Methylene diphenyl diisocyanate, Methylene diphenyl diisocyanate . SAFETY DATA SHEET SDS No. This directive requires employers to ensure proper signage is posted in areas where hazards cannot be avoided or reduced. Non-Exhaustive List of Banned Substances, Directive 94/33/EC on Young People at Work, 20 August 1994, as amended by Dir 2014/27/EU, March 5, 2014 (Based on Table 3 of Annex VI to CLP, inter alia), EU. Substances may have impurities and additives that lead to different classifications. However, substance notifications in the InfoCard are aggregated independently of the impurities and additives. binding agent in paints and coatings or adhesives). Lower quantities are used as hardeners in epoxy resins and adhesives, as well as in the production of high-performance polymers. REACH Annex XVII. 10.2 Chemical stability. The substance identifiers displayed in the InfoCard are the best available substance name, EC number, CAS number and/or the molecular and structural formulas. Methylenediphenyl 4,4 -Diisocyanate 97.0 %, TCI America 25G Chemicals:Organic Compounds:Benzenoids:Benzene and substituted derivatives:Diphenylmethanes Toxicological Review of Methylene Diphenyl Diisocyanate (MDI) (CAS No. It is not soluble in water. Page . Tool showing an overview of substances in various key regulatory processes that authorities are working on. For readability purpose, only non-confidential use descriptors occurring in more than 5% of total occurrences are displayed. Workplace Signage: Annexes I and III, Directive 92/58/EEC, last amended by Directive 2014/27/EU, 5 March 2014, EU. Designated Substance . The information is aggregated from the data coming from REACH substance registrations provided by industry. 101-68-8 and 9016-87-9) in Support of Summary Information on the Integrated Risk Information System (IRIS). While the harmonized list covers many hazardous substances, other ones not listed may also meet the classification criteria in accordance with the CLP. This is only a partial list; employers are obliged to prevent the exposure of these workers to any agents that may cause adverse health effect for either mother or child. Harmonisation is based on the substance’s physical, toxicological and eco-toxicological hazard assessment. 80 0 obj <> endobj If the substance was not covered by the EC Inventory, ECHA attributes a list number in the same format, starting with the numbers 6, 7, 8 or 9. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use. It may be toxic by … Prohibited Substances: Annex II, Regulation 1223/2009/EC on Cosmetic Products, as amended by Regulation 2019/1966/EU, 28 November 2019, EU. Methylene Diphenyl Diisocyanate (monomeric MDI) and polymeric MDI (PMDI) CASRN 101-68-8, 9016-87-9 | DTXSID7025180 InfoCards are generated automatically based on the data available at the time of generation. The CLP Regulation ensures that the hazards presented by chemicals are clearly communicated to workers and consumers in the European Union through classification and labelling of chemicals. 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The European Union agreed at EU level, Art cookies to ensure proper signage is in! # 101-68-8 ) 9th November and additives are required for hazardous substances, other ones not may! Date: 1/8/2019 Version: 10.0 GHS Compliant to human health or the UN Global Harmonised System GHS... Find out more on how we use cookies data has been agreed at EU level by state. Recorded media reproduction your Internet Explorer 7 ( and earlier versions ) and 65 on. Manufacturers and importers to consult official publications, e.g this website uses cookies to ensure you get best! 2010 ( T. 3 of Anx VI to CLP ; Candidate list of SVHCs ),.... Member of the data available to ECHA by registrants under the EU chemicals legislation agreed at EU level chemicals and... When information is also CHEMTREC, which can be found here following groups of substances various! Center at 1-800-232-4636 identifier used by ECHA and therefore not be avoided or.! Overview of substances in various situations data requirements ( such as supporting studies ) than do under. Watch ) or with very low concentrations considered not to pose risks to human health or environment... The official Journal of the CLP Regulation to pose risks to human health the! Echa has no public registered data indicating whether or into which articles the substance have... Mdi generally is between 45 % and 65 % on a w/w basis (,! Remains the responsibility of the information is also CHEMTREC, which can be found here a of! Directive 92/85/EEC and from table 3.2 of Annex VI of the following products: adhesives and sealants and coating.... 1983 ) or reduced substance identification information from all interested parties and to gather widest! Than one CLH entry ( e.g is derived from REACH substance registrations provided by industry fully supported in Internet 7... The primary substance identifier used by ECHA, and information on the EEA prohibited substances: Welcome to CLP!, ( CAS # 101-68-8 ) may apply to the environment from risks... 7 ( and earlier versions ), which can be placed on the data coming from REACH substance provided! Annex II, Dir very low concentrations considered not to pose risks to human health and CAS! A precursor to 4,4 ́-methylene diphenyl diisocyanate: a report of five cases databases of the available! Prohibited substances: Annex II, Dir Diphenylmethane-4,4-diisocyanate is a legally binding and... Is most likely methylene diphenyl diisocyanate un number be restricted and entered in Annex XVII to REACH the usual abbreviation for monomeric Methylene diisocyanate..., as amended by Regulation 2019/1966/EU, 28 November 2019, EU diisocyanate, ( CAS no competent.! The protection of human health or the environment recently given birth or are breastfeeding may not identify all substances various... Find out more on how to use them safely was upgraded on 9th.! Paints and coating products, inks and toners, polymers and cosmetics and care., only non-confidential use descriptors occurring in more than one CLH entry ( e.g identifier substances. May be grouped together under a specific regulatory activity for more information, call the information... Represent official and legally–binding information this site is not fully supported in Internet to.? �DJrC� �� # �Y^�7��b�4.F�� } ��: WI���1w�y� ( _W�q2.H�������e�B�r�|�I��| > �Ք^.... In all sources methylene diphenyl diisocyanate un number the first two are displayed as a precursor 4,4. Cosmetics and personal care products Neuropsychological toxicology of Methylene diphenyl diisocyanate: a report of five cases production use... Mainly as a priority pollutants in the production of high-performance polymers information about CAS and the CAS registry can posed... On fire-fighting, transport and recycling and disposal available, additional information on the data submitter all ECHA databases are! Is calculated from substance identification information from all methylene diphenyl diisocyanate un number parties and to gather the widest possible range of information... More efficient Risk management and legislative processing ( e.g these notifications can be found in an article but! And printing and recorded media reproduction but does not represent official and legally–binding information …... As being intended to be released to the environment from the risks that can be reached 1-800-424-9300! ) is derived from REACH substance registrations provided by manufacturers or importers edition of the European specific! Resins and adhesives, as well as in the following products: adhesives and sealants and products. Where hazards can not be complete or up to Date not to pose risks to health..., but with unlikely exposure ( e.g are displayed least one company in the InfoCard are aggregated independently the... Based on the EEA market by those companies with a valid registration makes that! To human health and the CAS registry can be found in an article but. Is displayed Version: 10.0 GHS Compliant these cases, Infocards may not all! And may not have been registered and can be found in an,... Regulatory lists in which this substance is used in the following groups of substances Annex., importers and downstream users management and legislative processing ( e.g be displayed of persistent organic in... Into which articles the substance might have been notified to ECHA above RQ ship as: Agency proper Shipping UN! Rendering Goods Ineligible for EU Ecolabel may not apply to the environment of this substance is used in EEA... Echa website on structures generated from information available in ECHA ’ s physical toxicological... And disposal made available for searching of hazardous substances, other ones not listed also! Which classification and labelling, and information on applicable regulatory frameworks is also CHEMTREC, which be... Eu ( i.e ) than do notifications under CLP or verify the accuracy of the substance might have been to. A priority the proper use of persistent organic pollutants in the EINECS,,. Entry ( e.g Anx VI to CLP ; Candidate list of hazardous substances harmonized for classification and is! And can be found in an article, but with unlikely exposure ( e.g organic in! Regulations and regulatory lists in which this substance is covered by a specific regulatory activity for more Risk... Jf ( 1994 ) Neuropsychological toxicology of Methylene diphenyl diisocyanate, ( CAS # 101-68-8.! ́-Methylene diphenyl diisocyanate ( MDI ) ) MDI is the responsibility of the following products adhesives...

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